Protein Modification Reagents
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Filtered Search Results
Medchemexpress LLC Mal-PEG4-vc-pab-dmea-pnu-159682 | 2259318-52-8 | 96.2% | 1559.62 | C74H98N10O27 | 25 MG
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Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a cleavable drug-linker conjugate used for antibody-drug conjugate (ADC) research. It couples a maleimide-terminated PEG4 valine-citrulline (VC) self-immolative PAB linker to a potent cytotoxic payload to enable antibody conjugation and controlled release of the payload in target cells.
- Cleavable maleimide-PEG4 val-cit self-immolative linker enabling intracellular release.
- Includes a reactive maleimide moiety for thiol conjugation to antibodies.
- Supplied as a research-grade drug-linker conjugate for ADC development workflows.
- Provided with batch-specific certificate of analysis reporting HPLC purity and assay results.
- Soluble in common organic solvents such as DMSO for conjugation reactions.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 2183440-27-7 | endo-BCN-PEG12-acid | Broadpharm793.945 | C38H67NO16 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 50mg | 354974898
endo-BCN-PEG12-acid | Broadpharm | 2183440-27-7793.945 | C38H67NO16 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 50mg | 354974898
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Grainger Closed End Peg Rack 19.88 L Blue PK6
The Carlisle Closed End Peg Rack is a 19-7/8" long metal peg rack with closed ends. It has 20 evenly spaced pegs that are 1/2" in diameter and protrude 1-1/4" from the rack. The rack is made from steel with a durable powder coat finish and can hold up to 50 lbs per linear foot. This versatile rack can be used for retail displays, workshops, garages, basements, and more to hang tools, hardware, accessories, apparel and other items with holes or hooks. It comes with mounting hardware for easy installation on walls or pegboards. The closed ends prevent items from sliding off the ends of the rack.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Mal-PEG4-PFP ester | 1415800-42-8 | 95.4% | 511.39 g·mol-1 | C21H22F5NO8 | 1 G
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Mal-PEG4-PFP ester is a noncleavable ADC linker that incorporates a maleimide reactive group, a four-unit polyethylene glycol (PEG4) spacer, and a pentafluorophenyl (PFP) activated ester. It is supplied for research use to enable conjugation of payloads to thiol- or amine-containing biomolecules.
- Noncleavable ADC linker with a maleimide reactive group.
- Four-unit PEG spacer for increased solubility and flexibility.
- PFP ester activated for efficient coupling to amines.
- Molecular weight 511.39 g·mol-1.
- Chemical formula C21H22F5NO8.
- Purity 95.4% (as supplied).
- Storage: pure form -20°C for 3 years, 4°C for 2 years; in solvent -80°C for 6 months, -20°C for 1 month.
- Intended for research use only; not for human or clinical use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Mpro inhibitor N3 (hemihydrate) | 99.9% | 689.80 | 25 MG
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This product is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 of 16.77 μM. It specifically inhibits Mpro from various coronaviruses, including SARS-CoV and MERS-CoV, and demonstrates inhibitory activity against HCoV-229E, FIPV, and MHV-A59 with respective IC50 values of 4.0 μM, 8.8 μM, and 2.7 μM.
- Potent inhibitor of SARS-CoV-2 Mpro.
- Exhibits broad-spectrum inhibition against multiple coronaviruses.
- Demonstrates inhibition against various HCoVs.
- Able to penetrate cells to inhibit virus replication in embryos.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Boc-Aminooxy-PEG4-NH2 | 2062663-66-3 | 95.0% | C13H28N2O7 | 50 MG
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Boc-Aminooxy-PEG4-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates the degradation of target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 134179-38-7 | N3-PEG(4)-NH2 | Chem-Impex | MFCD00269874 | 218.257 | C8H18N4O3 | 97.000 | NCCOCCOCCOCCN=[N+]=[N-] | 100mg | 490843607
N3-PEG(4)-NH2 | Chem-Impex | 134179-38-7 | MFCD00269874 | 218.257 | C8H18N4O3 | 97.000 | NCCOCCOCCOCCN=[N+]=[N-] | 100mg | 490843607
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Dspe-m-peg-nhs | 99.4% | 3,400 (average) | 50 MG
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DSPE-m-PEG-NHS (MW 3400) is a PEGylated phospholipid bearing an N-hydroxysuccinimide (NHS) ester. Supplied as a white-to-off-white solid, it is used to formulate liposomes and lipid nanoparticles and enables amine-reactive surface conjugation for targeted delivery applications such as DNA and mRNA vaccines.
- Provides an NHS-reactive ester for efficient conjugation to primary amines.
- Facilitates PEGylation to improve nanoparticle stability and circulation time.
- Suitable for liposome and lipid nanoparticle formulation.
- Average molecular weight about 3,400 for consistent performance.
- Stable as a powder when stored at -20°C, supporting extended shelf life.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Med Vet International Timolol Maleate (Generic Timoptic) Solution, 0.5%, 5mL
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Timolol Maleate is a generic version of Timoptic. Ophthalmic Timolol is in a class of medications called beta-blockers. It is an ophthalmic solutions that is used to decrease pressure in the eye.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 557756-85-1 | Fmoc-NH-PEG4-CH2CH2COOH | ChemScene | MFCD06656472 | 487.549 | C26H33NO8 | 96.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 100mg | 642097511
Fmoc-NH-PEG4-CH2CH2COOH | ChemScene | 557756-85-1 | MFCD06656472 | 487.549 | C26H33NO8 | 96.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 100mg | 642097511
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 1345681-74-4 | Mal-PEG1-PNP-carbonate | Broadpharm350.283 | C15H14N2O8 | 98.000 | [O-][N+](=O)c1ccc(OC(=O)OCCOCCN2C(=O)C=CC2=O)cc1 | 100mg | 573896599
Mal-PEG1-PNP-carbonate | Broadpharm | 1345681-74-4350.283 | C15H14N2O8 | 98.000 | [O-][N+](=O)c1ccc(OC(=O)OCCOCCN2C(=O)C=CC2=O)cc1 | 100mg | 573896599
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383728 TOS-PEG2-THP 250MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383729 S R S -AHPC-PEG5-BO 250MG
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Medchemexpress LLC 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-(2-azidoethoxy)ethoxy]ethyl] hexahydro-2-oxo- | 1910803-72-3 | 97.0% | 100 MG
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Biotin-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group, which allows it to undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Click chemistry reagent with an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Medchemexpress LLC Biotin-PEG4-Amide-C6-Azide | 1006592-62-6 | 99.1% | C27H49N7O7S | 25 MG
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Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne group molecules. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN group molecules.
- PEG-based PROTAC linker
- Click chemistry reagent with azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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